Presentation Details
| Hospitalization outcomes from venous thromboembolism in cancer patients: An analysis of the national inpatient sample data from 2016 to 2019 Youjin oh, Alejandro Vallejo, Alexandra Sueldo, Lina james, Angelo Caputi Zuniga, Ayobami Olafimihan, Ekrem Turk. John H.Stroger Jr Hospital, Chicago, IL, USA |
Abstract
Background: Thromboembolic events significantly impact cancer patients, leading to increased mortality and extended hospital stays. Identifying the factors contributing to these outcomes is vital for enhancing patient care and prognosis. Objectives: This study explores risk factors linked to inpatient mortality and length of hospital stay (LOS) in cancer patients hospitalized for thromboembolic events. Methods: We analyzed 675,407 admissions for venous thromboembolism (VTE) from the HCUP-NIS database (2016-2019), among which admissions with any type of cancer diagnosis were selected. Subgroup was selected for admissions with at least one of ten high VTE risk cancers: malignancy of prostate, bladder, uterine, pancreas, brain, stomach, lung and bronchus, breast, ovary, and colon. We examined how factors like age (categories: <40, 40-65, >65), gender, race (White, Black, Hispanic, Asian, and Pacific Islanders), household income estimated by patient’s ZIP code (by quartiles), admission type (elective vs. non- elective), and hospital size classified by bed size, location and teaching status (small, medium, large) impacted mortality and LOS. Logistic regression was used to assess mortality, while linear regression analyzed LOS correlations. Results: The admissions for VTE among all types of cancers were 52,650. The median age was 70 (Interquartile ranges (IQR) 61-78) with a female population of 50.9%. The ethnicity distribution of those patients was found to be 75% White, 16% Black, 7% Hispanic, and 2% Asian and Pacific Islanders. The inpatient mortality rate was 5.8%, with a median LOS of 4 days (IQR 2-6 days). Significant mortality risk factors included age 40-65 (Odds ratio (OR)
1.68), age >65 (OR 1.86), male gender (OR 1.08), Asian or Pacific Islander ethnicity (OR 1.46), large hospital size (OR 1.41), and elective admission (OR 1.29). Non-White ethnicities experienced longer LOS. Higher income was associated with shorter LOS, as were smaller hospital sizes and non-elective admissions. The subgroup (n=29,986) was not significantly different for age, gender, mortality, and LOS compared to all admissions. The proportion of ethnic groups was 74% for White, 17% for Black, 6% for Hispanic, and 2% for Asian and Pacific Islanders. Asian and Pacific Islanders had higher mortality, as did patients in medium
and large hospitals, and those with elective admissions. The White population had a shorter LOS, whereas large hospital and elective admissions were associated with a longer LOS. Conclusions: In summary, our study highlights some risk factors associated with increased inpatient mortality and LOS among cancer patients admitted for thromboembolic events. These findings suggest male patients, those over the age of 40, and those of Asian descent have a significant association with higher inpatient mortality. The non-White population and lower- income population were also associated with longer LOS. Recognition of these factors may
help healthcare providers streamline resources and enhance the quality of care for potentially vulnerable patient populations.
No part of this publication may be reproduced, distributed, or transmitted in any form or by any means, including photocopying, recording, or other electronic or mechanical methods, without the prior written permission of the author.
1.68), age >65 (OR 1.86), male gender (OR 1.08), Asian or Pacific Islander ethnicity (OR 1.46), large hospital size (OR 1.41), and elective admission (OR 1.29). Non-White ethnicities experienced longer LOS. Higher income was associated with shorter LOS, as were smaller hospital sizes and non-elective admissions. The subgroup (n=29,986) was not significantly different for age, gender, mortality, and LOS compared to all admissions. The proportion of ethnic groups was 74% for White, 17% for Black, 6% for Hispanic, and 2% for Asian and Pacific Islanders. Asian and Pacific Islanders had higher mortality, as did patients in medium
and large hospitals, and those with elective admissions. The White population had a shorter LOS, whereas large hospital and elective admissions were associated with a longer LOS. Conclusions: In summary, our study highlights some risk factors associated with increased inpatient mortality and LOS among cancer patients admitted for thromboembolic events. These findings suggest male patients, those over the age of 40, and those of Asian descent have a significant association with higher inpatient mortality. The non-White population and lower- income population were also associated with longer LOS. Recognition of these factors may
help healthcare providers streamline resources and enhance the quality of care for potentially vulnerable patient populations.
No part of this publication may be reproduced, distributed, or transmitted in any form or by any means, including photocopying, recording, or other electronic or mechanical methods, without the prior written permission of the author.